Formulation and Evaluation of Sustain Release Matrix Tablet of Aceclofenac

Authors

  • Ravi Sharma Department of Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan
  • Mayank Bansal Department of Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan
  • Alok Garg HOD Production Department, Chemosyn Limited, Mumbai, Maharashtra
  • Vikas Agarwal Department of Pharmaceutical Chemistry, Jaipur College of Pharmacy, Jaipur, Rajasthan
  • Deeksha Sharma Department of Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan.

Abstract

The current study aimed to generate Aceclofenac sustained-release matrix tablets with the use of mimosa pudica mucilage as well as povidone. Since aceclofenac is so popular as a centrally acting muscle relaxant, we've decided to make sustained-release tablets out of it. Evaluations of in-vitro release studies and other characteristics such as thickness, appearance, weight variation, hardness, friability, as well as content uniformity were performed after compression. Results of all evaluation parameters were in limit and satisfactory. Stability study of the optimized formulation was also done for 3 months and the formulation had shown satisfactory stability.

Key words: matrix tablet, muscle relaxant, stability study.

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Published

2023-03-31

How to Cite

Ravi Sharma, Mayank Bansal, Alok Garg, Vikas Agarwal, & Deeksha Sharma. (2023). Formulation and Evaluation of Sustain Release Matrix Tablet of Aceclofenac. International Journal of Health Advancement and Clinical Research (tz), 1(1). Retrieved from https://ijhacr.com/index.php/ijhacr/article/view/2

Issue

Vol. 1 No. 1 (2023): January-March

Section

Articles