An Overview on Microparticle Drug Delivery Systems

Abstract

To improve effectiveness, tolerance, and patient compliance, microparticles are used as multiunit drug delivery methods with well-defined physiological as well as pharmacokinetic advantages. They have a diameter between 0.1 μm and 200 μm. This review explores the key aspects of microparticulate drug delivery systems, their advantages as well as disadvantages. There are various methods like Single Emulsion Process, Phase Separation, Fluidized Bed Coating, Double Emulsion Process, Spray Drying and Solvent / Emulsion Extraction Process which can be used for the manufacturing of microparticles and various evaluation parameters. There are many challenges with microparticles which we have discussed here and potential application of microparticles in pharmaceutical industry.