A Review on Sustained Release Matrix Tablets
Keywords:
Matrix tablet, Friability, Swelling index, Therapeutic efficacy.Abstract
A sustain-release matrix tablet is a pharmaceutical dosage form designed to deliver medication over an extended period. These tablets are engineered to provide a controlled and consistent release of active ingredients, ensuring therapeutic efficacy while reducing dosing frequency and minimizing side effects. This review article will delve into the key aspects of sustain-release matrix tablets, including their benefits and drawbacks. We have discussed about various evaluation such as tablet dimension, hardness, friability, drug content uniformity, weight variation, swelling index as well as in vitro dissolution test. Sustained release matrix tablets have broad applications in many therapeutic areas where consistent and prolonged drug release is essential for maintaining therapeutic efficacy, improving patient compliance, and minimizing side effects. The choice to use such tablets depends on the specific drug, patient needs, and the desired therapeutic outcome.