Formulation And Evaluation of Fast Dissolving Tablets of Piroxicam Using Various Concentration of Different Super Disintegrating Agents

Abstract

Fast-dissolving tablets (FDTs) offer several advantages and disadvantages, making them a unique pharmaceutical dosage form suitable for specific applications. The current study attempted to create and assess a fast-dissolving tablet containing Piroxicam employing several superdisintegrants in order to increase its therapeutic efficiency along with patient compliance. Piroxicam is a nonsteroidal anti-inflammatory medicine used to treat osteoarthritis, rheumatoid arthritis, as well as ankylosing spondylitis. It is classed as a Class II drug in the Biopharmaceutical drugs Classification system. Here are some of the key advantages and disadvantages of fast-dissolving tablets. Directed compression method was utilized for the preparation of FDTs and nine formulations were formulated using Cross Povidone, Pre gelatinized starch & Microcrystalline Cellulose at different concentration. Different types of evaluation parameters are mentioned below. Results of all the evaluation parameters of all formulations were satisfactory and within limit. It may be concluded that a mouth dissolving tablet of Piroxicam can be produced utilizing Cross Povidone to increase therapeutic efficiency and patient compliance.